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Article

Assays for Detection of Telomerase Activity

2011-03-15

Abstract excerpt

Progressive loss of the telomeric ends of chromosomes caused by the semi-conservative mechanism of DNA replication is an important timing mechanism which controls the number of cells doubling. Telomerase is an enzyme which elongates one chain of the telomeric DNA and compensates for its shortening during replication. Therefore, telomerase activity serves as a proliferation marker. Telomerase activity is not detect...

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Identifiers and source

Literature Corpus work
454e8ab7-99e4-52d1-8f5d-667a244f3665
DOI
10.32607/20758251-2011-3-1-48-68
Open publication

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