Article

Presence of minimal residual disease determined by next-generation sequencing is not a reliable prognostic biomarker in children with acute lymphoblastic leukemia

2024-09-03

Abstract excerpt

<h4>Background: </h4> The definition of molecular remission by more sensitive methodologies became a cornerstone for stratification and therapeutic decisions in pediatric acute lymphoblastic leukemia (ALL). The role of next-generation sequencing (NGS) for minimal residual disease (MRD) assessment is still under consideration. <h4>Methods: </h4>: Fifty pediatric patients treated with ALL-IC-BFM-2002 protocol were...

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Literature Corpus work: 452f4065-0e29-55fa-b2b0-b17193fccf27
DOI: 10.22541/au.172536128.83797266/v1

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