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In Silico Metabolic Modeling Reveals Potential Muscle Metabolite Markers of Insulin Resistance in Newly Diagnosed Diabetic Patients

2020-12-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Type 2 diabetes mellitus (T2DM) is a challenging and globally ubiquitous metabolic disease caused by insulin resistance. Skeletal muscle is the major insulin-sensitive tissue that plays a great role in blood sugar homeostasis. Dysfunction of muscle metabolism is implicated in the disturbance of glucose hemostasis and the development of insulin resistance and T2DM...

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Literature Corpus work
4505b5df-0bc0-5c7b-a17a-f9fe89cead02
DOI
10.21203/rs.3.rs-130707/v1
Open publication

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In Silico Metabolic Modeling Reveals Potential Muscle Metabolite Markers of Insulin Resistance in Newly Diagnosed Diabetic PatientsDOI 10.21203/rs.3.rs-130707/v1
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