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Unraveling the molecular heterogeneity in type 2 diabetes: A potential subtype discovery followed by metabolic modeling

2020-08-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Type 2 diabetes mellitus (T2DM) is a complex multifactorial disease with a high prevalence worldwide. Insulin resistance and impaired insulin secretion are the two major abnormalities in the pathogenesis of T2DM. Skeletal muscle is responsible for over 75% of the glucose uptake and plays a critical role in T2DM. Here, we sought to provide a better understanding of...

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Literature Corpus work
002face3-ff61-5d50-8d60-68c5fafa9be0
DOI
10.21203/rs.2.20464/v7
Open publication

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