Article

MdrDB: Mutation-induced drug resistance DataBase

2022-10-24

Abstract excerpt

<h4> A bstract </h4> Mutation-induced drug resistance – where the efficacy of drugs is diminished by structural changes in proteins – presents a significant challenge to drug development and the clinical treatment of disease. Understanding the effects of mutation on protein-ligand binding affinities is a key step in developing more effective drugs and therapies, but as a research community we are currently hind...

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Literature Corpus work: 45053cdd-0a1e-5d00-bd39-2006c80ce420
DOI: 10.1101/2022.10.20.513118

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