Article

Hepatocyte PPARγ contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice

2022-06-08

Abstract excerpt

<h4>Background & Aims</h4> Non-alcoholic steatohepatitis (NASH) is associated with obesity and increased expression of hepatic peroxisome proliferator-activated receptor γ (PPARγ) in humans. Although we previously showed that the expression of PPARγ in hepatocytes contributes to the development NASH in lean mice, the relevance of hepatocyte PPARγ in the development of NASH associated with obesity is still poorly...

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Literature Corpus work: 44d5c155-57c7-5e31-b115-966cc98ada12
DOI: 10.1101/2022.06.06.494901

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