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Article

Optimization and validation of a quadruplex real-time PCR assay for the diagnosis of diphtheria

2019-04-06

Abstract excerpt

Diphtheria is caused by toxigenic strains of Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis . For diagnostic purposes, species identification and detection of toxigenic strains (diphtheria toxin (tox)-positive strains) is typically performed using end-point PCR. A faster quadruplex real-time PCR (qPCR) was recently developed (De Zoysa et al . J Med Microbiol. 2016 6...

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Literature Corpus work
44b07d5c-95b0-591e-97e3-33747ad48301
DOI
10.1101/600270
Open publication

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Optimization and validation of a quadruplex real-time PCR assay for the diagnosis of diphtheriaDOI 10.1101/600270
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