Article
Emergence and molecular characterisation of non-toxigenic tox gene-bearing Corynebacterium diphtheriae biovar mitis in the United Kingdom, 2003-2012.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 5 Jun 2014
Zakikhany K, Neal S, Efstratiou A
Abstract excerpt
Non-toxigenic Corynebacterium diphtheriae have become increasingly recognised as emerging pathogens across Europe causing severe invasive disease. A subset of non-toxigenic C. diphtheriae are ‘non-toxigenic tox gene-bearing’ (NTTB) strains; these strains are genotypically toxpositive, but do not express the protein. The circulation of NTTB strains was first observed during the 1990s upsurge of diphtheria in...
Topics
- Adolescent
- Adult
- Aged
- Animals
- Cats
- Child
- Communicable Diseases, Emerging
- Corynebacterium diphtheriae
- Diphtheria
- Diphtheria Toxin
- Female
- Genes, Bacterial
- Genetic Variation
- Genotype