Article

TP53 signature score predicts prognosis and immune response in triple-negative breast cancer

2022-03-03

Abstract excerpt

<title>Abstract</title> <p>Purpose Triple-negative breast cancer (TNBC) is considered a heterogeneous population and achieving a pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is an only prognostic factor. Previously, the <italic>TP53</italic> signature (<italic>TP53</italic>sig)-score, an expression profile of 33 genes, is reportedly predictive of the prognosis of all types of early-stag...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 44a8fef5-4459-5ec8-b2a6-1239efdcf818
DOI: 10.21203/rs.3.rs-1233460/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TP53 signature score predicts prognosis and immune response in triple-negative breast cancerDOI 10.21203/rs.3.rs-1233460/v1Read

Differences in prognosis and efficacy of chemotherapy by p53 expression in triple-negative breast cancer.Semantic proximity Read

Combination of Immune-Related Network and Subtype-Specific Analysis Define a Three- Gene Panel for Predicting Prognosis of Triple-Negative Breast CancerSemantic proximity Read

<i>TP53</i> mutations promote immunogenic activity in breast cancerSemantic proximity Read

Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapiesSemantic proximity Read

New Biomarkers and Treatment Advances in Triple-Negative Breast CancerSemantic proximity Read

A Comprehensive Immunologic Portrait of Triple-Negative Breast CancerSemantic proximity Read

Combination of Immune-Related Network and Molecular Typing Analysis Defines a Three-Gene Signature for Predicting Prognosis of Triple-Negative Breast CancerSemantic proximity Read

IRSN-23 Gene Diagnosis Predicts Response to Neoadjuvant Chemotherapy and Refines Breast Cancer Subtype Classification (Prospective Analyses)Semantic proximity Read

Identification of an immune cell infiltration-related gene signature for prognosis prediction in triple-negative breast cancer.Semantic proximity Read

Immune Microenvironment-Related Genes Contribute to Clinical Prognosis in Patients with Triple-Negative Breast CancerSemantic proximity Read

P53 immunohistochemistry is an ideal surrogate marker for TP53 mutation and a predictor of early metastasis in breast cancer: Real-world analysisSemantic proximity Read

A scoring screening system based on machine learning for immunotherapy beneficiaries in triple-negative breast cancerSemantic proximity Read