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Combination of Immune-Related Network and Molecular Typing Analysis Defines a Three-Gene Signature for Predicting Prognosis of Triple-Negative Breast Cancer

25 Oct 2022

Abstract excerpt

Recent breakthroughs in immune checkpoint inhibitors (ICIs) have shown promise in triple-negative breast cancer (TNBC). Due to the intrinsic heterogeneity among TNBC, clinical response to ICIs varies greatly among individuals. Thus, discovering rational biomarkers to select susceptible patients for ICIs treatment is warranted. A total of 422 TNBC patients derived from The Cancer Genome Atlas (TCGA) database and...

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Bioinformatics and Genomic Networks
Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36358906
DOI: 10.3390/biom12111556

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