Article

Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium

2024-04-16

Abstract excerpt

Estradiol (E2) and relaxin (Rln) are steroid and polypeptide hormones, respectively, with important roles in the female reproductive tract, including myometrium. Some actions of Rln, which are mediated by its membrane receptor RXFP1, require or are augmented by E2 signaling through its cognate nuclear steroid receptor, estrogen receptor alpha (ERα). In contrast, other actions of Rln act in opposition to the effect...

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Literature Corpus work: 44a3406b-a896-50e2-abad-d80bb0d9a037
DOI: 10.1101/2024.04.15.589654

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