Article

Assessment of the reproducibility and inter-site transferability of the murine direct splenocyte mycobacterial growth inhibition assay (MGIA)

2021-02-15

Abstract excerpt

Tuberculosis (TB) vaccine candidates must be tested for safety and efficacy using preclinical challenge models prior to advancement to human trials, because of the lack of a validated immune correlate or biomarker of protection. New, unbiased tools are urgently needed to expedite the selection of vaccine candidates at an early stage of development and reduce the number of animals experimentally infected with virul...

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Literature Corpus work: 44945154-3e60-5a0e-9e26-b1b43f0a4852
DOI: 10.1101/2021.02.14.431105

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