Article

CycleMix: Gaussian Mixture Modeling of the Cell Cycle

2025-02-15

Abstract excerpt

The cell cycle is a crucial component of many biological processes, including cancer, tissue repair, and inflammation. However, due to the heterogeneity of this cycle it has been difficult to assess the extent of proliferation in clinical tissues. Single-cell RNAseq (scRNAseq) and spatial transcriptomics enables high resolution measurement of gene expression enabling the classification of individual cells into the...

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Literature Corpus work: 4476f99e-cb97-5438-a5f3-d04cb5c4fe3c
DOI: 10.1101/2025.02.11.637734

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