Article

CoPhaser: generic modeling of biological cycles in scRNA-seq with context-dependent periodic manifolds

2025-12-26

Abstract excerpt

Biological cycles are ubiquitous cellular processes operating across a wide range of time scales. Fundamental cycles such as the cell cycle, circadian rhythms, or the segmentation clock occur cell-autonomously and are typically coupled to other cellular processes, including cell-type identity, metabolic states, and disease-associated programs. In single-cell transcriptomics (scRNA-seq), disentangling these continu...

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Literature Corpus work: 579ee431-d0b5-50dc-b334-6553385fd25d
DOI: 10.64898/2025.12.24.696376

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