Article

Identification and functional role of endothelial isoforms of the transcription factor ERG

2018-01-01

Abstract excerpt

The ETS transcription factor ERG is highly expressed in endothelial cells (EC) and has a crucial role in controlling homeostasis and angiogenesis. ERG drives expression of genes which promote EC identity, monolayer integrity, survival and angiogenesis. Studies in non-EC have identified multiple ERG isoforms that display functional differences. Notably, some ERG isoforms are phosphorylated through the MAPK pathway,...

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Literature Corpus work: 44680d98-bc00-5a35-8d4d-9a21bc6fa420
DOI: 10.25560/68034

Open publication

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