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Article

Sequence-function correlations and dynamics of ERG isoforms. ERG8 is the black sheep of the family.

Biochimica et biophysica acta - 1 Feb 2016

Hoesel Bastian, Malkani Naila, Hochreiter Bernhard, Basílio José, Sughra Kalsoom, Ilyas Muhammad, Schmid Johannes A

Abstract excerpt

The transcription factor ERG is known to have divergent roles. On one hand, it acts as differentiation factor of endothelial cells. On the other hand, it has pathological roles in various cancers. Genomic analyses of the ERG gene show that it gives rise to several isoforms. However, functional differences between these isoforms, representing potential reasons for distinct effects in diverse cell types have not...

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Identifiers

PMID: 26554849
DOI: 10.1016/j.bbamcr.2015.10.023
PMCID: PMC4716293

Genes

ERG
NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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