Article

Carbon and Nitrogen Isotopic Signatures as Metabolic Biomarkers of Nodal Metastasis and Recurrence in Oral Squamous Cell Carcinoma

2026-03-24

Abstract excerpt

<h4>Background: </h4> /Objectives: Oral squamous cell carcinoma (OSCC) exhibits substantial biological heterogeneity, and current clinicopathological risk stratification incompletely reflects tumor metabolic behavior. Stable isotope ratio mass spectrometry enables quantitative assessment of carbon and nitrogen isotopic composition, potentially capturing cumulative metabolic reprogramming associated with tumor aggr...

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Literature Corpus work: 445654e0-1508-59c9-986b-7a2eab7ed1f7
DOI: 10.20944/preprints202603.1862.v1

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