Article

Loss of heterozygosity and absence of MAX immunostaining in a prolactinoma associated with multiple endocrine neoplasia type 5 (MEN5)

2025-10-07

Abstract excerpt

<title>Abstract</title> <p> Multiple endocrine neoplasia type 5 (MEN5) is an emerging syndrome caused by germline pathogenic variants involving the <italic>MYC Associated Factor X</italic> ( <italic>MAX</italic> ) gene. Affected individuals typically have pheochromocytomas, often bilateral, at a relatively early age. In <italic>MAX</italic> pheochromocytoma cohorts, pituitary adenomas are rarely reported....

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Literature Corpus work: 44534aa1-941c-5491-b678-ba1f24192698
DOI: 10.21203/rs.3.rs-7760856/v1

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