Article

Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry

2026-01-20

Abstract excerpt

<title>Abstract</title> <p> Pheochromocytomas and paragangliomas (PPGLs) are rare, genetically diverse tumors originating from the adrenal medulla or extra-adrenal paraganglia, respectively. Defining a pathogenic variant is critical for patient management and family surveillance, particularly for the 35–40% of patients carrying a germline variant, including those in the <italic>TMEM127</italic> gene. However,...

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Literature Corpus work: cd04bd50-02e8-5e98-ae4e-8d999c7fd6ac
DOI: 10.21203/rs.3.rs-8553860/v1

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