Article

Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry

2026-02-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Context</bold> : Pheochromocytomas and paragangliomas (PPGLs) are rare, genetically diverse tumors originating from the adrenal medulla or extra-adrenal paraganglia, respectively. It is critically important to establish the pathogenic status of genetic variants, especially for the 35-40% patients carrying a germline change, as it impacts patient management and family surveillan...

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Literature Corpus work: 9f103b6b-0b9f-59ac-a4ea-d4133db04086
DOI: 10.21203/rs.3.rs-8553860/v2

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