Article

IL-1 modulation preserves biomolecular, structural and functional integrity of the somatosensory cortex after fetal inflammation

2025-11-07

Abstract excerpt

<title>Abstract</title> <p>Perinatal inflammation, often caused by infection, is strongly linked with lifelong disability. Human and experimental studies identify interleukin-1 (IL-1), a pro-inflammatory cytokine, as a key mediator. We tested the hypothesis that systemic administration of IL-1 receptor antagonist (IL-1Ra) could attenuate cortical inflammation and improve neuronal development in late gestation fet...

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Literature Corpus work: 43f207b0-1d38-5fbc-9c59-77f89a6695d5
DOI: 10.21203/rs.3.rs-7882525/v1

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IL-1 modulation preserves biomolecular, structural and functional integrity of the somatosensory cortex after fetal inflammationDOI 10.21203/rs.3.rs-7882525/v1Read

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