Article
Identification of biological mechanisms underlying a multidimensional ASD phenotype using machine learning.
Translational psychiatry - 28 Jan 2020
Asif Muhammad, Martiniano Hugo F M C, Marques Ana Rita, Santos João Xavier, Vilela Joana, Rasga Celia, Oliveira Guiomar, Couto Francisco M, Vicente Astrid M
Abstract excerpt
The complex genetic architecture of Autism Spectrum Disorder (ASD) and its heterogeneous phenotype makes molecular diagnosis and patient prognosis challenging tasks. To establish more precise genotype-phenotype correlations in ASD, we developed a novel machine-learning integrative approach, which seeks to delineate associations between patients' clinical profiles and disrupted biological processes, inferred from...
Topics
Join the communities discussing this publication.