Article

Syndecan-1 is overexpressed in human thoracic aneurysm but is dispensable for the disease progression in vivo

2021-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Glycosaminoglycans (GAGs) pooling has been considered since long as one of the histopathological characteristics defining thoracic aortic aneurysm (TAA) together with smooth muscle cells (SMCs) apoptosis and elastin fibers degradation. However, few information is provided about GAGs composition or potential implication in TAA pathology. Syndecan-1 (Sdc-1) is a heparan sulfate proteoglycan that i...

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Literature Corpus work: 437bf601-8709-5f87-99d5-07680955ef33
DOI: 10.1101/2021.12.16.471096

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