Article

An lp17-encoded small non-coding RNA with a potential regulatory role in mammalian host adaptation by the Lyme disease spirochete

2020-11-06

Abstract excerpt

The bacterial agent of Lyme disease, Borrelia burgdorferi, relies on an intricate gene regulatory network to transit between the disparate Ixodes tick vector and mammalian host environments. We recently reported that a B. burgdorferi mutant lacking an intergenic region of lp17 displayed attenuated murine tissue colonization and pathogenesis due to altered antigen expression. In this study, a more detailed chara...

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Literature Corpus work: 601ac6f7-6ea8-5af3-aee8-7e400ae396b5
DOI: 10.1101/2020.11.06.371013

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