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<i>Coxiella burnetii</i> small RNA 12 binds CsrA regulatory protein and transcripts for the CvpD type IV effector, regulates pyrimidine and methionine metabolism, and is necessary for optimal intracellular growth and vacuole formation during infection

2019-06-21

Abstract excerpt

Coxiella burnetii is an obligate intracellular gammaproteobacterium and zoonotic agent of Q fever. We previously identified 15 small non-coding RNAs (sRNAs) of C. burnetii . One of them, named CbsR12 ( C oxiella b urnetii s mall R NA 12 ) is highly expressed during growth in axenic medium and becomes even more dominant during infection of cultured mammalian cells. Secondary structure predictions of CbsR12 re...

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Literature Corpus work
c6e9983e-7691-56ec-94eb-c6e50bea7cc8
DOI
10.1101/679134
Open publication

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