Article

Infection and transmission of SARS-CoV-2 depends on heparan sulfate proteoglycans

2020-08-18

Abstract excerpt

The current pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and outbreaks of new variants highlight the need for preventive treatments. Here we identified heparan sulfate proteoglycans as attachment receptors for SARS-CoV-2. Notably, neutralizing antibodies against SARS-CoV-2 isolated from COVID-19 patients interfered with SARS-CoV-2 binding to heparan sulfate proteoglycans, which m...

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Literature Corpus work: 4327f721-d64e-5857-920d-69e40600091e
DOI: 10.1101/2020.08.18.255810

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