Article

miR-377 regulates the tumorous behaviors of prostate cancer cells by targeting of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4

2023-08-03

Abstract excerpt

<h4>Background: </h4> The MYC gene is one of the regulatory and proto-oncogenic genes overexpressed in most prostate cancers (PCa). Studies have shown that abnormal expression of microRNAs is involved in the onset and development of many different types of human cancer, including prostate cancer. <h4>Methods: </h4> and result: In this study, we first evaluated targeting the effect of miR-377 on MYC by luciferase...

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Literature Corpus work: 931f91b2-4d5d-5984-a92b-2c9e3f63292a
DOI: 10.21203/rs.3.rs-3215226/v1

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