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IQGAP2 regulates blood-brain barrier immune dynamics

2023-02-08

Abstract excerpt

Brain endothelial cells (BECs) play an important role in maintaining central nervous system (CNS) homeostasis through blood-brain barrier (BBB) functions. BECs express low baseline levels of adhesion receptors, which limits entry of leukocytes. However, the molecular mediators governing this phenotype remain mostly unclear. Here, we explored how infiltration of immune cells across the BBB is influenced by the scaf...

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Identifiers and source

Literature Corpus work
42b7c81b-43d2-5e69-89c9-62c743b2ce3e
DOI
10.1101/2023.02.07.527394
Open publication

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IQGAP2 regulates blood-brain barrier immune dynamicsDOI 10.1101/2023.02.07.527394
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