Article

ALKBH5 mediated RNA N6-methyladenosine demethylation protects against myocardial I/R induced injury via FSP1 dependent inhibition of ferroptosis

2024-12-09

Abstract excerpt

In the realm of myocardial ischemia/reperfusion (I/R) injury, the intricate interplay between RNA modifications and cellular responses remains a subject of intense investigation. Here, we elucidate a pivotal role of ALKBH5-mediated RNA N6-methyladenosine (m6A) demethylation in safeguarding against myocardial I/R-induced injury through the inhibition of ferroptosis, a regulated form of cell death characterized by i...

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Literature Corpus work: 428393a5-6f52-53cd-ab96-8ac0b5d47366
DOI: 10.22541/au.173372242.25727947/v1

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