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N6-methyladenine demethylase ALKBH5 alleviates cardiomyocytes apoptosis via modulating m6A/SIRT1 manner

2022-08-19

Abstract excerpt

Recent studies have shown that the potential regulatory role of N 6 -methyladenine (m 6 A) modification may affect the occurrence and development of various cardiovascular diseases. However, the regulatory mechanism of m 6 A modification on myocardial ischemia reperfusion injury (MIRI) is rarely reported. A mice model of myocardial I/R was established by ligation and perfusion of the left anterior descending coron...

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Literature Corpus work
99835531-df42-5bba-83d3-58ff96d8f81e
DOI
10.21203/rs.3.rs-1960313/v1
Open publication

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N6-methyladenine demethylase ALKBH5 alleviates cardiomyocytes apoptosis via modulating m6A/SIRT1 mannerDOI 10.21203/rs.3.rs-1960313/v1
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