Article

Toward overcoming pyrethroid resistance in mosquito control: the role of sodium channel blocker insecticides

2023-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Diseases spread by mosquitoes lead to death of 700,000 people each year. The main way to reduce transmission is vector control by biting prevention with chemicals. However, the most commonly used insecticides lose efficacy due to the growing resistance. Voltage-gated sodium channels (VGSCs), membrane proteins responsible for the depolarizing phase of an action potential, are targeted by a broad...

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Literature Corpus work: 4267863c-844b-5706-abea-3015cd764cae
DOI: 10.1101/2023.03.29.534712

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