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Identification of MTHFD2 as a Prognostic Factor and Evaluation of its Role in Macrophage Polarization in Kidney Renal Clear Cell Carcinoma by Pan-Cancer Analysis

2024-04-05

Abstract excerpt

<title>Abstract</title> <p>The enzyme methylenetetrahydrofolate dehydrogenase-cyclohydrolase (MTHFD2) in the mitochondrial folate cycle plays oncogenic roles in different types of cancers; nonetheless, the function of MTHFD2 in tumor immunity and underlying mechanisms are unclear. A systematic bioinformatics analysis and lab experiments were conducted to explore the role in the tumor microenvironment (TME). Eleva...

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Literature Corpus work
5c8a1993-4b1e-52be-bdab-23357d3f0622
DOI
10.21203/rs.3.rs-4196758/v1
Open publication

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Identification of MTHFD2 as a Prognostic Factor and Evaluation of its Role in Macrophage Polarization in Kidney Renal Clear Cell Carcinoma by Pan-Cancer AnalysisDOI 10.21203/rs.3.rs-4196758/v1
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