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Article

Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms

27 Jun 2016

Abstract excerpt

Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle. This can be generalised or localised to certain muscle groups, and involvement of the bulbar and respiratory muscles can be life threatening. The pathogenesis of myasthenia...

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PMID: 27408701
DOI: 10.12688/f1000research.8206.1

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