Article

Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies

2020-11-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The genome of SARS-CoV-2 is susceptible to mutations during viral replication due to the errors generated by RNA-dependent RNA polymerases. These mutations enable the SARS-CoV-2 to evolve into new strains. Viral quasispecies emerge from de novo mutations that occur in individual patients. In combination, these sets of viral mutations provide distinct genetic fingerprints that...

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Literature Corpus work: 4211f0cc-c14e-53f2-826a-57f2aaeb65c3
DOI: 10.1101/2020.11.02.20224816

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