Article

Assessment of Liver Fibrosis by Transient Elastography in Children and Young Adults with Sickle Cell Disease With and Without Iron Overload

2024-01-30

Abstract excerpt

<h4>Objectives: </h4> Transfusion-associated iron overload may cause liver fibrosis. We compared transient elastography (TE) and aspartate aminotransferase-platelet ratio index (APRI), non-invasive markers for hepatic fibrosis, to percutaneous liver biopsy in children and young adults with sickle cell disease (SCD). <h4>Methods:</h4> Subjects had serum ferritin was >500 ng/mL and lacked history of viral hepatitis....

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Literature Corpus work: 420e3cdc-b579-5c58-98b6-ac012558c4ca
DOI: 10.22541/au.170665296.63352709/v1

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