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Article

Non-invasive assessment of liver fibrosis in C282Y homozygous HFE hemochromatosis.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jun 2015

Legros Ludivine, Bardou-Jacquet Edouard, Latournerie Marianne, Guillygomarc'h Anne, Turlin Bruno, Le Lan Caroline, Désille Yoann, Lainé Fabrice, Moirand Romain, Brissot Pierre, Deugnier Yves, Guyader Dominique

Abstract excerpt

BACKGROUND & AIMS: C282Y homozygotes with serum ferritin (SF) levels >1000 μg/L and/or increased serum transaminase levels are at risk of severe F3/F4 fibrosis. Current practical guidelines recommend liver biopsy in such individuals. This prospective observational cohort study aimed to evaluate non-invasive alternative means such as hyaluronic acid (HA) and transient elastography (TE) for the assessment of severe...

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Source

Identifiers

PMID: 25495562
DOI: 10.1111/liv.12762

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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