Article
Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study.
Alimentary pharmacology & therapeutics - 1 Aug 2016
Kim R G, Nguyen P, Bettencourt R, Dulai P S, Haufe W, Hooker J, Minocha J, Valasek M A, Aryafar H, Brenner D A, Sirlin C B, Loomba R
Abstract excerpt
BACKGROUND: Limited data exist on the clinical presentation and non-invasive detection of liver fibrosis in adults with homozygous Z genotype alpha-1 antitrypsin (AAT) deficiency. AIMS: To compare demographic, biochemical, histological and imaging data of AAT deficient patients to normal-control and biopsy-proven non-alcoholic fatty liver disease (NAFLD) patients, and to assess the diagnostic accuracy of magnetic...
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