Article

Synovial Transcriptome Profiling for Predicting Biological Treatment Response in Rheumatoid Arthritis: A Feasibility study

2024-08-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Disease-Modifying Anti-Rheumatic Drug (DMARD) treatment fails to achieve clinical remission in a substantial proportion of patients with rheumatoid arthritis (RA). Patient-derived synovial tissue (ST)-signatures, thought to determine this heterogeneity of treatment responses, can be studied by single-cell RNA sequencing (scRNA-seq). <h4>Study aims</h4> The first aim was to o...

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Literature Corpus work: 11063de8-9bd8-5265-bf1b-4bd189774a51
DOI: 10.1101/2024.08.28.24312608

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