Article

A multi-omics approach identifies a blood-based miRNA signature of cognitive decline in two large observational trials

2022-06-17

Abstract excerpt

Identifying individuals before the onset of overt symptoms is a key prerequisite for the prevention of Alzheimer’s disease (AD). A wealth of data reports dysregulated microRNA (miRNA) expression in the blood of individuals with AD, but evidence in individuals at subclinical stages is sparse. In this study, a qPCR analysis of a prioritised set of 38 candidate miRNAs in the blood of 830 healthy individuals from the...

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Literature Corpus work: 41cb549f-b79a-5900-893f-fdc24a0e2282
DOI: 10.1101/2022.06.17.22276532

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