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Literature-Identified Serum miRNA Signatures for Cognitive Decline: Integrated Analysis and Machine-Learning Diagnostics in Alzheimer’s Disease

2026-01-28

Abstract excerpt

<title>Abstract</title> <p>Background Because identification of preclinical Alzheimer’s disease (AD) still relies on costly or invasive A/T/N biomarkers, we systematically integrated published case-control studies to identify differentially expressed serum microRNAs (miRNAs) associated with cognitive function in patients with AD, and validated their diagnostic performance in the large public cohort GSE120584. Me...

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Literature Corpus work
19bba56e-5cbc-5d0f-b39f-a17a33a1c99c
DOI
10.21203/rs.3.rs-8620145/v1
Open publication

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Literature-Identified Serum miRNA Signatures for Cognitive Decline: Integrated Analysis and Machine-Learning Diagnostics in Alzheimer’s DiseaseDOI 10.21203/rs.3.rs-8620145/v1
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