Article

BlpC-mediated selfish program leads to rapid loss of <i>Streptococcus pneumoniae</i> clonal diversity during infection

2022-08-06

Abstract excerpt

<h4>SUMMARY</h4> Chromosomal barcoding and high-throughput sequencing were used to investigate the population dynamics of Streptococcus pneumoniae . During infant mouse colonization, >35-fold reduction in diversity and expansion of a single clonal lineage was observed within 1 day post-inoculation. This loss of diversity was not due to immune factors, host microbiota or exclusively because of genetic drift. Rath...

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Literature Corpus work: 41b30ad1-f170-5d97-98e2-b4fd6c64f737
DOI: 10.1101/2022.08.05.500807

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