Article

<i>De novo</i> basecalling of m <sup>6</sup> A modifications at single molecule and single nucleotide resolution

2023-11-13

Abstract excerpt

<h4>ABSTRACT</h4> RNA modifications hold pivotal roles in shaping the fate and function of RNA molecules. Although nanopore sequencing technologies have proven successful at transcriptome-wide detection of RNA modifications, current algorithms are limited to predicting modifications at a per-site level rather than within individual RNA molecules. Herein, we introduce m 6 ABasecaller , an innovative method enab...

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Literature Corpus work: 41ae4fe8-da7d-5935-83c2-ca414a960d54
DOI: 10.1101/2023.11.13.566801

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