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Article

MRT-ModSeq - Rapid Detection of RNA Modifications with MarathonRT.

Journal of molecular biology - 15 Nov 2023

Araujo Tavares Rafael de Cesaris, Mahadeshwar Gandhar, Wan Han, Pyle Anna Marie

Abstract excerpt

Chemical modifications are essential regulatory elements that modulate the behavior and function of cellular RNAs. Despite recent advances in sequencing-based RNA modification mapping, methods combining accuracy and speed are still lacking. Here, we introduce MRT-ModSeq for rapid, simultaneous detection of multiple RNA modifications using MarathonRT. MRT-ModSeq employs distinct divalent cofactors to generate 2-D...

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PMID: 37802215
DOI: 10.1016/j.jmb.2023.168299

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PRUNE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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