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Exploring the Genetic and Genomic Connection Underlying Neurodegeneration with Brain Iron Accumulation and the Risk for Parkinson’s Disease

2022-09-29

Abstract excerpt

<h4>Background</h4> Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation and the presence of axonal spheroids in the brain. In Parkinson’s Disease (PD), iron accumulation is a cardinal feature of degenerating regions in the brain and seems to be a key player in mechanisms that precipitate cell death. <h4>Objectives</h4>...

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Literature Corpus work
415f39a3-3278-52ca-ac09-7132392e9719
DOI
10.1101/2022.09.28.22280461
Open publication

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