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Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

7 May 2014

Abstract excerpt

Perturbation of iron distribution is observed in many neurodegenerative disorders, including Alzheimer's and Parkinson's disease, but the comprehension of the metal role in the development and progression of such disorders is still very limited. The combination of more powerful brain imaging techniques and faster genomic DNA sequencing procedures has allowed the description of a set of genetic disorders...

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PMID: 24847269
DOI: 10.3389/fphar.2014.00099

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