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Article

Neurodegeneration with brain iron accumulation: from genes to pathogenesis.

Seminars in pediatric neurology - 1 Sept 2006

Hayflick Susan J

Abstract excerpt

Neurodegeneration with brain iron accumulation comprises a clinically and genetically heterogeneous collection of disorders that share key features. These include progressive neurological disease accompanied by high basal ganglia iron and axonal dystrophy. To date, 2 genetic forms have been associated with mutations in PANK2 and PLA2G6, both of which encode proteins that are critical to membrane integrity. The...

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Identifiers

PMID: 17101457
DOI: 10.1016/j.spen.2006.08.007

Genes

PANK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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