Article
Lipoprotein (a) up-regulates the expression of the plasminogen activator inhibitor 2 in human blood monocytes.
Blood - 15 Feb 2001
Buechler C, Ullrich H, Ritter M, Porsch-Oezcueruemez M, Lackner K J, Barlage S, Friedrich S O, Kostner G M, Schmitz G
Abstract excerpt
Elevated plasma lipoprotein (a) (Lp[a]) and cardiac events show a modest but significant association in various clinical studies. However, the influence of high Lp(a) on the gene expression in blood monocytes as a major cell involved in atherogenesis is poorly described. To identify genes influenced by elevated serum Lp(a), the gene expression was analyzed on a complementary DNA microarray comparing monocytes...
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