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Lipoprotein Apheresis: An Established Therapeutic Modality for Homozygous Familial Hypercholesterolemia Patients Refractory to PCSK9 Inhibitors: A Case Report and Literature Review

2024-07-29

Abstract excerpt

<title>Abstract</title> <p>Homozygous familial hypercholesterolemia (HoFH), is a rare genetic disorder characterized by dual mutations in the low-density lipoprotein receptor (LDLR) gene, leading to dysfunctional or absent LDLRs, often accompanied by severe premature Atherosclerotic Cardiovascular Disease (ASCVD) and exhibiting refractoriness to aggressive pharmacological interventions. Double filtration plasmaph...

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Literature Corpus work: 09e0ab26-5476-543e-95d1-bd342c337012
DOI: 10.21203/rs.3.rs-4662053/v1

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