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Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern

2021-08-12

Abstract excerpt

<h4>ABSTRACT</h4> To understand the nature of the antibody response to SARS-CoV-2 vaccination, we analyzed at single cell level the B cell responses of five naïve and five convalescent people immunized with the BNT162b2 mRNA vaccine. Convalescents had higher frequency of spike protein specific memory B cells and by cell sorting delivered 3,532 B cells, compared with 2,352 from naïve people. Of these, 944 from naï...

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Literature Corpus work
413d8067-4091-5b9e-9505-6ee8349de3ed
DOI
10.1101/2021.08.12.456077
Open publication

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Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concernDOI 10.1101/2021.08.12.456077
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