Article
Translating Knowledge Into Therapy for Acute Kidney Injury.
Seminars in nephrology - 1 Jan 2018
de Caestecker Mark, Harris Raymond
Abstract excerpt
No therapies have been shown to improve outcomes in patients with acute kidney injury (AKI). Given the high morbidity and mortality associated with AKI this represents an important unmet medical need. A common feature of all of the therapeutic development efforts for AKI is that none were driven by target selection or preclinical modeling that was based primarily on human data. This is important when considering...
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